Bone health in bipolar disorder: A study protocol for a case-control study in Australia

Abstract

Little is known about the bone health of adults with bipolar disorder, aside from evidence purporting bone deficits among individuals with other mental illnesses, or those taking medications commonly used in bipolar disorder. In this paper, we present the methodology of a case-control study which aims to examine the role of bipolar disorder as a risk factor for bone fragility. Methods and analysis Men and women with bipolar disorder (∼200 cases) will be recruited and compared with participants with no history of bipolar disorder (∼1500 controls) from the Geelong Osteoporosis Study. Both cases and controls will be drawn from the Barwon Statistical Division, south-eastern Australia. The Struct..